This match sees a meeting of teams enduring contrasting fortunes.
Oldham sit comfortably in fifth while Colchester are nervously in 21st, helping to explain why Latics are 7/10 for victory here with Colchester priced at 4/1 with the draw 13/5.
Oldham have won four of their last six. Lee Johnson’s men are 10 points off fourth-placed Preston so their aim will be to build upon the play-off place they currently occupy.
However Tony Humes will be hoping to pick up some points, with his side’s away form most respectable - they were beaten for the first time in four away matches by Sheffield United at Bramall Lane in midweek.
Oldham have only kept three clean sheets at SportsDirect.com Park so far this season which should mean that whatever the final outcome, a bet on both teams to score could pay dividends.
Top Tip: Both teams to score at 5/6